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Cell-signaling profile. A, STAT3 and STAT5 phosphorylation following treatment with GIFT15 or GMCSF and IL-15 at 15 min and 5 h. B, STAT3 and STAT5 phosphorylation time course. C, GIFT15 activation of major MAPK (p38/Erk/Jnk) and PI3K/Akt signaling pathways.
