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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: Bioorg Med Chem. 2016 May 5;24(24):6354–6369. doi: 10.1016/j.bmc.2016.05.003

Figure 2.

Figure 2

A) FtsZ monomers polymerize in the presence of GTP, forming protofilaments. B) Protofilaments line up at the center of the cell to form the highly dynamic Z-ring, which is anchored to the bacterial cell membrane by FtsA and ZipA. FtsZ monomers readily exchange with FtsZ molecules incorporated into the Z-ring. C) Contraction of the Z-ring leads to invagination of the cell membrane. D) Septation is completed and the Z-ring dissipates.