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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: Bioorg Med Chem. 2016 May 5;24(24):6354–6369. doi: 10.1016/j.bmc.2016.05.003

Figure 3.

Figure 3

(A) Normal cells divide and remain a short length. (B) and (C) Inhibition of FtsZ causes filamentation. Cells continue to grow and elongate, but cannot divide. Reprinted with permission from Huang, Q.; Kirikae, F.; Kirikae, T.; Pepe, A.; Amin, A.; Respicio, L.; Slayden, R. A.; Tonge, P. J.; Ojima, I., Targeting FtsZ for Antituberculosis Drug Discovery: Noncytotoxic Taxanes as Novel Antituberculosis Agents. J. Med. Chem. 2006, 49 (2), 463–466. Copyright 2012 American Chemical Society.