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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: Bioorg Med Chem. 2016 May 5;24(24):6354–6369. doi: 10.1016/j.bmc.2016.05.003

Figure 6.

Figure 6

Movement of helix 7 favors the high affinity state over the low affinity state. Reprinted with permission from Elsen, N. L.; Lu, J.; Parthasarathy, G.; Reid, J. C.; Sharma, S.; Soisson, S. M.; Lumb, K. J., Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity. J. Am. Chem. Soc. 2012, 134 (30), 12342–5. Copyright 2012 American Chemical Society.