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Antitubercular activity of lead benzimidazoles against drug sensitive and drug resistant strains
| Compound | (MIC99 μg/mL) M. tuberculois strains
|
||||
|---|---|---|---|---|---|
| H37Rv | NHN382 | TN587 | W210 | NHN20 | |
|
| |||||
| SB-P3G2 | 0.63 | 1.25 | 1.25 | 1.25 | - |
| SB-P8B2 | 0.39 | 0.31 | 0.16 | 0.63 | - |
| SB-P17G-C2 | 0.06 | 0.06 | 0.13 | 0.06 | - |
| SB-P20G3 | 0.16 | 0.16 | 0.16 | 0.16 | - |
| SB-P17G-A20 | 0.16 | 0.16 | 0.16 | 0.16 | - |
| SB-P17G-A33 | 0.39 | 0.37 | 0.31 | 0.47 | 0.39 |
| SB-P17G-A38 | 0.31 | 0.31 | 0.31 | 0.47 | 0.24 |
| SB-P17G-A42 | 0.18 | 0.16 | 0.24 | 0.31 | 0.16 |
