Table 2.
Incidence of nausea, retching, and vomiting in dogs administered maropitant (MRP; 1 mg/kg BW), metoclopramide (MCP; 0.5 mg/kg BW), or normal saline (SAL; 0.1 mL/kg BW) SQ, 45 min prior to morphine (0.5 mg/kg BW) and acepromazine (0.05 mg/kg BW). The time to first emetic event, number of emetic events per dog [median (minimum — maximum)] and the incidence of pain after injection are also reported. Different superscript letters indicate significant differences between groups
| Variable | MRP (n = 21) | MCP (n = 21) | SAL (n = 21) | P-value |
|---|---|---|---|---|
| Nausea | 16/21 (76%)a | 15/21 (71%)a | 17/21 (81%)a | 0.769 |
| Retching | 1/21 (4.8%)a | 6/21 (29%)b | 9/21 (43%)b | 0.016 |
| Vomiting | 0/21 (0%)a | 8/21 (38%)b | 15/21 (71%)c | < 0.001 |
| Emetic events | — | 1.0 (1.0 to 3.0)a | 1.0 (1.0 to 3.0)a | 0.591 |
| Time to first emesis (min) | — | 3.9 (2.0 to 11.5)a | 7.1 (3.8 to 10.2)a | 0.093 |
| Pain | 10/21 (48%)a | 2/21 (9.5%)b | 1/21 (4.8%)b | < 0.001 |
MRP — maropitant; MCP — metoclopramide; SAL — saline.