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. 2016 Aug 23;35(30):5536–5550. doi: 10.1002/sim.7077

Figure 1.

Figure 1

The type I error rate P0,δB(RA) to reject H A as function of δ B when applying the simultaneous stopping rule or separate stopping rule for boundaries v 1,v 2 satisfying ((2)) (dashed curves) or the simultaneous stopping rule for improved boundaries v1,v2 = v 2 where v1 solves ((4)) (solid curves) for O'Brien Fleming boundaries (left graph) and Pocock boundaries (right graph). No futility bound is applied (l 1=−). The horizontal dashed lines show the nominal α level and the levels corresponding to v1 and v 1.