Fig. 1.

Heatmap based on the expression profile of 161 miRNAs in RMS. Skeletal muscle samples (red) cluster together showing high expression of a group of miRNA which contains “muscle specific” miR-1, miR-133 and miR-206. Myoblast sample is in separate (tomato red). The histology is color-coded as follows: ARMS_PAX3-FOXO1 (khaki), ARMS_PAX7-FOXO1 (dark green), ERMS (sky blue) and ARMS negative (blue). Fusion gene positive (light khaki) and negative (navy) patients mainly cluster into two separate groups. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)