Table 1.

Unadjusted Mortality Rates by AP Exposure

Antipsychotic	No. Patients Died/Total (%)	Total Person-years	Mortality Rate per 100 Person-years (95% CI)
Intention-to-treat analysis
Haloperidol	60/282 (21.3)	122.5	49.0 (37.4–63.0)
Other typical AP	20/140 (14.3)	64.0	31.3 (19.1–48.3)
Olanzapine	113/837 (13.5)	386.3	29.3 (24.1–35.2)
Quetiapine fumarate	462/5270 (8.8)	2488.8	18.6 (16.9–20.3)
Risperidone	164/1155 (14.2)	529.5	31.0 (26.4–36.1)
Other atypical AP	13/193 (6.7)	91.3	14.2 (7.6–24.3)
Exposure-only analysis
Haloperidol	35/282 (12.4)	68.7	50.9 (35.5–70.9)
Other typical AP	8/140 (5.7)	32.5	24.6 (10.6–48.5)
Olanzapine	54/837 (6.5)	240.1	22.5 (16.9–29.3)
Quetiapine	268/5270 (5.1)	1754.2	15.3 (13.5–17.2)
Risperidone	96/1155 (8.3)	340.8	28.2 (22.8–34.4)
Other atypical AP	7/193 (3.6)	59.1	11.8 (4.8–24.4)

Abbreviation: AP, antipsychotic.