Table 1. Phenotypic analysis of wild type and Del(Hotair)-/- skeletons at post-natal day 22 (P22).
| wt | Del(Hotair)+/- | Del(Hotair)-/- | |
|---|---|---|---|
| (n = 11) | (n = 11) | (n = 10) | |
| Lumbar vertebrae | |||
| L6 | 1 | 1 | 1 |
| L6/S1* | 2 | 1 | 1 |
| L5 | 8 | 9 | 8 |
| Wrist | |||
| normal | 11 | 11 | 10 |
| ill-formed | 0 | 0 | 0 |
| Ankle | |||
| normal | 11 | 11 | 10 |
| ill-formed | 0 | 0 | 0 |
* Mixed identity
Various control and mutant specimen were scored for having either five lumbar vertebrae (L5), six (L6) or a mixed L5-6/S1 vertebra. The mesopodial bones (wrist and ankle) were found normal in shape and number in all cases.