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. 2016 Dec 15;11(12):e0167179. doi: 10.1371/journal.pone.0167179

Table 1. Dup15q syndrome participant characteristics.

Older participants tested in Orlando did not undergo cognitive testing, as age-appropriate cognitive tests were not available. N/A = not available.

Group Age (months) Site Gender Meds Genetics Epilepsy Verbal developmental quotient (VDQ) Nonverbal developmental quotient (NVDQ)
Dup15q 99.9 UCLA Female risperidone isodicentric no 43 47
Dup15q 42.5 UCLA Male none isodicentric no 12 32
Dup15q 44.5 UCLA Male none isodicentric no 72 64
Dup15q 28.1 UCLA Female none isodicentric no 39 46
Dup15q 42.8 UCLA Female levetiracetam isodicentric yes 6 4
Dup15q 55.9 UCLA Female none interstitial no 105 100
Dup15q 230.1 UCLA Female zoloft interstitial no N/A 56
Dup15q 54.2 UCLA Male none interstitial no 8 24
Dup15q 57 UCLA Male none isodicentric no 48 46
Dup15q 143.8 UCLA Female levetiracetam isodicentric yes 7 12
Dup15q 106.1 UCLA Male no anticonvulsant interstitial no 33 34
Dup15q 15.8 UCLA Female no anticonvulsant isodicentric no 48 79
ASD 61.2 UCLA Male Focalin, risperdone N/A no 51 48
ASD 26.6 UCLA Male none N/A no 19 45
ASD 39.3 UCLA Male none N/A no 33 46
ASD 63 UCLA Male none N/A no 43 41
ASD 28.8 UCLA Male none N/A no 28 52
ASD 53.2 UCLA Female risperidone N/A no 56 51
ASD 48.6 UCLA Male none N/A no 17 49
ASD 32.3 UCLA Male none N/A no 25 43
ASD 58.5 UCLA Female zoloft N/A no 103 74
ASD 98.7 UCLA Male melatonin N/A no 21 50
TD 57 UCLA Female none N/A no 122 94
TD 54 UCLA Male none N/A no 98 97
TD 29 UCLA Male none N/A no 131 157
TD 55 UCLA Male none N/A no 140 107
TD 38.8 UCLA Female none N/A no 145 149
TD 43.8 UCLA Male none N/A no 109 115
TD 40.8 UCLA Male none N/A no 141 113
TD 59.6 UCLA Female none N/A no 127 103
TD 59.6 UCLA Male none N/A no 112 117
Dup15q 93.2 Orlando Male rufinamide 1200 mg b.i.d., levetiracetam 2000 mg b.i.d., lacosamide 40 mg b.i.d., Epidiolex (canibidiol) 7 mL x2 isodicentric yes 39 37
Dup15q 108.2 Orlando Male no anticonvulsant interstitial no N/A N/A
Dup15q 147.3 Orlando Female lamotrigine 300 mg b.i.d. lacosamide 100mg b.i.d. felbamate 1200mg/800mg/1000mg isodicentric yes 14 N/A
Dup15q 110.5 Orlando Male no anticonvulsant isodicentric no 12 21
Dup15q 117.5 Orlando Female no anticonvulsant interstitial no 37 44
Dup15q 65.45 Orlando Male levetiracetam 500mg AM 750mg PM lamotrigine 100 mg b.i.d. isodicentric yes 9 13
Dup15q 44.9 Orlando Female no anticonvulsant interstitial no 11 27
Dup15q 47 Orlando Female no anticonvulsant isodicentric no N/A N/A
Dup15q 81.2 Orlando Male valproic acid 250mg b.i.d. oxcarbazepine 300mg b.i.d. isodicentric yes N/A N/A
Dup15q 48.7 Orlando Male no anticonvulsant isodicentric no N/A N/A
Dup15q 384 Orlando Female valproic acid interstitial yes N/A N/A
Dup15q 161.6 Orlando Male no anticonvulsant interstitial no N/A N/A
Dup15q 29.4 Orlando Male no anticonvulsant isodicentric no 36 29
Dup15q 111.7 Orlando Female no anticonvulsant interstitial no 26 24
Dup15q 86 Orlando Female no anticonvulsant isodicentric no N/A N/A