Figure 5.

Cardiac Fibrosis

(A) Picrosirius red staining of heart sections (original magnification ×1.25; scale = 1 mm; zoom insert image scale = 0.5 mm). (B) Quantification of total cardiac fibrosis of the scar, LV, right ventricular, and septum regions. (C) Scar thickness for each MI group. n = 10, 10, 9, and 8 for sham, MI, MI/AAVGFP and MI/AAVAng-(1-9), respectively. Data presented as mean ± SEM. *p <0.05, **p <0.01, ***p <0.001 versus sham region; ^#p <0.05, ^##p <0.01 versus MI and MI/AAVGFP region. Abbreviations as in Figures 1 and 2.