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. 2016 Dec 15;11(12):e0167947. doi: 10.1371/journal.pone.0167947

Table 3. Interventions at national level & at PML and expected effects.

Hospital based interventions Duration Proportion of deaths prevented (expected)
1 Doctor with MSc in Paediatrics March 2001-Oct. 2008 7% reduction in child mortality per unit increase in paediatricians [18] and from 10–18% per week to 6–8% per week [19]; Reduction of total mortality from 80.5 to 70.5 deaths per 1000 admissions [20].
1 Specialist October 2003 to 2009
1 Doctor with MSc in Paediatric (Specialist from 2008) 2003 to present
2 Doctors with Diploma in Child Health June 2006 for 1–1½ years
2 Specialists October 2007 to present
1 Specialist October 2008 to present
Emergency Unit 2005 to present From 10–18% per week to 6–8% [19]
Housemen Rotations May 2007 to present -
WHO Pocket Book on Paediatrics 2007 to present 2.4%, using antibiotic guidelines [21]*
HIV Clinic (ARVs) 2007 to present 75% reduction in mortality in < 2 [22]
Medical Officers Rotations 2008 to present -
CMAM Training 2009 to present 55% Case Fatality (SAM) [23]
Special Care Babies Unit 2009 to present 61% survival for VLBW babies [24]
ETAT Training 2010 to present From 10–18% per week to 6–8% [19]*; From 80.5 to 70.5 deaths per 1000 admissions [20]*
Paediatric Nurses Rotation 2012 to present -
Interventions at national level Duration Proportion of deaths prevented (expected)
IMNCI Training 2000; 2004 to Present 33% of all U5M [6], 13% [25]
Penta-valent vaccine (Hib) 2002 to present 4% of U5M [6]
Measles vaccine and measles campaigns 2002, 2006, 2010 and 2013 (yearly) 1% of U5M [6]; 20% reduction in mortality from non-specific effects [26]
Child Health Record Book & Danger signs 2002 to present 3%, 6%,13% of all U5M [6] $
Anaemia Control Strategy 2003 (1 year) 24% reduced risk of death per 1-g/dL increase in Hb [27]
National Health Insurance Scheme 2003 to present 7% decrease in infant mortality, in US [28];46% lower risk of death in Burkina Faso [29]
Antiretroviral drugs for PMTCT 2003 to Present 2% of all U5M [6]
Change in Malaria Treatment protocol 2004 to present 5% [6], & from 29%-16% [30] of U5M
Maternal & Child Health Promotion Week 2004 to present (yearly) 3%, 6%,13% of all U5M [6] $
Vitamin A supplementation for under-fives 2005 to present 2% of U5M [6]
ITN distribution 2005–2007, 2011, 2012 7% of U5M [6]
CMAM (outpatients management) 2008 to present -
CMAM (Inpatient management) 2009 to present 55% reduction from SAM (CF)[23]
Child Health Policy 2010 to present -
Rotavirus Vaccine 2012 to present 30–39% reduction in deaths in 1–2 year olds, 29–33% in1-4 year olds [31]
Pneumococcal Vaccine 2012 to present 16% of all-cause mortality [32]
Zinc Supplementation in Diarrhoea 2012 to present 4% of U5M [6]

ACTs = Artemisinin Combination Therapies; ARVs = Anti-retrovirals; CMAM = Community-based Management of Acute Malnutrition in the community; ETAT = Emergency Triage Assessment and Treatment; Hib = Hemophilus influenza b; IMNCI = Integrated Management of Neonatal and Childhood Illnesses; ITN = Insecticide Treated Net; WHO = World Health Organisation; U5M = under-five mortality; SAM = Severe Acute Malnutrition; CF = Case Fatality; VLBW = very low birth weight infant (birth weight less than 1500g (up to and including 1499g)

* as part of multiple interventions

$Selected interventions