Table 1. Derlin-1 immunohistochemical scores in relation to clinicopathological characteristics.
| Variables | Case (n) | Derlin-1 expression | P Value | |
|---|---|---|---|---|
| Negative (%) | Positive (%) | |||
| Age (years)a | 0.758 | |||
| <70 | 81 | 29(35.8) | 52(64.2) | |
| ≥70 | 63 | 21(33.3) | 42(66.7) | |
| Gender | 0.831 | |||
| Female | 39 | 13(33.3) | 26(66.7) | |
| Male | 105 | 37(35.2) | 68(64.8) | |
| Tumor stageb | <0.005 | |||
| pTa~1 | 46 | 24(52.2) | 22(47.8) | |
| pT2~4 | 98 | 26(26.5) | 72(73.5) | |
| Histological grade | <0.001 | |||
| Low | 51 | 46(90.2) | 5(9.8) | |
| High | 93 | 4(4.3) | 89(95.7) | |
| lymph node metastasis | <0.001 | |||
| Negative | 89 | 45(50.6) | 44(49.4) | |
| Positive | 55 | 5(9.1) | 50(90.9) | |
a Median, 67 years; range, 33–92 years
b Staging and grading according to the WHO 2004 classification system.