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. 2016 Dec 15;11(12):e0168505. doi: 10.1371/journal.pone.0168505

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© 2016 Pabbidi et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — Effects of Raf-1 inhibition (10 μM GW5074) on zint-β₂-AR stimulation of I_Ca,L in +PKA (A), -PKA (B) atrial myocytes. A; In +PKA myocytes, GW5074 (30 min) had no significant effect on zint-β₂-AR stimulation of I_Ca,L. B; In -PKA myocytes, zint-β₂-AR stimulation of I_Ca,L was enhanced compared to control responses (A) and GW5074 significantly inhibited zint-β₂-AR stimulation of I_Ca,L. Numbers in parentheses indicate the number of myocytes studied. * = P<0.05.