Table 2. Body weight, heart weight, right ventricular weight, left ventricular weight, and citrate synthase activity in the soleus in control and exercised rats exposed to intermittent hypoxia or room air for 14 days.

	CON			IHCON			EXE			IHEXE
	Veh	Zinc	TPEN	Veh	Zinc	TPEN	Veh	Zinc	TPEN	Veh	Zinc	TPEN
Body weight (BW, g)
Day 0	535.2±14.4	552.2±19.4	533.4±27.0	516.0±20.3	539.4±27.9	536.0±18.1	441.0±35.2†,‡	446.0±11.8	456.0±14.0	431.2±9.7†,‡	447.0±15.9	469.4±28.5
Day 14	494.6±21.3*	500.8±18.4*	477.4±24.5*	454.8±15.0*	474.4±18.4*	454.8±13.2*	437.4±29.8	419.4±9.5*	418.6±11.7*	402.4±7.7*,†	395.4±17.5*	423.2±24.3*
Heart
Right ventricle weight (RVW, g)	0.28±0.01	0.28±0.02	0.26±0.02	0.25±0.02	0.27±0.02	0.23±0.02	0.25±0.02	0.23±0.02	0.22±0.02	0.24±0.02	0.23±0.02	0.27±0.03
Left ventricle weight (LVW, g)	1.06±0.04	1.06±0.05	0.99±0.05	0.88±0.05†	0.98±0.03	0.91±0.04	0.99±0.04	0.92±0.04	0.86±0.05	0.87±0.04†	0.86±0.05	0.90±0.05
Heart weight (HW, g)	1.34±0.05	1.34±0.05	1.25±0.06	1.13±0.06†	1.26±0.04	1.14±0.05	1.24±0.05	1.15±0.06	1.08±0.06	1.11±0.05†	1.09±0.06	1.17±0.07
RVW/BW (mg/g)	0.57±0.01	0.56±0.02	0.56±0.02	0.57±0.02	0.58±0.02	0.52±0.02	0.57±0.02	0.56±0.04	0.55±0.04	0.61±0.04	0.59±0.04	0.67±0.04
LVW/BW (mg/g)	2.12±0.11	2.11±0.09	2.12±0.09	2.06±0.08	2.10±0.09	2.09±0.09	2.28±0.09	2.23±0.09	2.12±0.09	2.16±0.09	2.19±0.08	2.26±0.07
HW/BW (mg/g)	2.68±0.11	2.66±0.09	2.68±0.09	2.63±0.09	2.68±0.09	2.61±0.09	2.85±0.09	2.79±0.10	2.67±0.10	2.77±0.10	2.78±0.09	2.93±0.08
Soleus
Citrate synthase activity (U/mg protein)	0.278±0.01	0.291±0.01	0.292±0.03	0.247±0.02	0.259±0.01	0.278±0.02	0.410±0.02†,‡	0.430±0.02	0.416±0.02	0.429±0.03†,‡	0.463±0.04	0.401±0.01

Values are presented as means±SEM. CON, controls; IHCON, intermittent hypoxia; EXE, exercise; IHEXE, IH interspersed with EXE; Veh, vehicle injection; zinc, zinc chloride injection; TPEN, N,N,N',N'-tetrakis(2-pyridylmethyl) ethylenediamine injection.

*p<0.05 compared with day 0;

^†p<0.05 compared with CON-Veh;

^‡p<0.05 compared with IHCON-Veh.