Table 2. Cox proportional hazards model for recurrence-free survival and overall survival (n = 262).
A. Univariate analysis | |||||||
Recurrence-free survival | Overall survival | ||||||
Variable | HR | 95% CI | P value | HR | 95% CI | P value | |
Age | (50< vs. ≤50) | 1.8 | 0.8–5.4 | 0.19 | 2.2 | 0.8–9.4 | 0.16 |
Tumor size | (2cm< vs. ≤2cm) | 3.7 | 1.8–8.3 | 0.0003 | 3.9 | 1.7–10.2 | 0.002 |
Nodal status | (Positive vs. Negative) | 4.4 | 2.1–9.4 | <0.0001 | 4.3 | 1.9–10.7 | 0.0006 |
pStage | (III vs. I and II) | 6.8 | 3.1–14.1 | <0.0001 | 9.5 | 4.0–21.9 | <0.0001 |
Nuclear grade | (3 vs. 1 and 2) | 1.1 | 0.5–2.4 | 0.87 | 1.0 | 0.4–2.4 | 0.93 |
Ki-67 | (20%< vs. ≤20%) | 1.2 | 0.4–5.1 | 0.76 | 1.0 | 0.3–4.1 | 0.96 |
Basal-like status | (Basal-like vs. Non-basal-like) | 0.9 | 0.3–2.9 | 0.78 | 1.3 | 0.4–8.1 | 0.72 |
BRCAness status | (BRCAness vs. Non-BRCAness) | 2.6 | 1.1–7.8 | 0.03 | 3.1 | 1.1–13.2 | 0.04 |
Chemotherapy | (Anthra vs. Non-anthra) | 0.4 | 0.2–1.6 | 0.19 | 0.4 | 0.1–2.6 | 0.29 |
(Anthra vs. No Treatment) | 0.8 | 0.4–1.9 | 0.64 | 0.3 | 0.1–0.8 | 0.02 | |
B. Multivariate analysis | |||||||
Recurrence-free survival | Overall survival | ||||||
Variable | HR | 95% CI | P value | HR | 95% CI | P value | |
pStage | (III vs. I and II) | 9.5 | 4.1–21.1 | <0.0001 | 21.3 | 7.7–60.1 | <0.0001 |
BRCAness status | (BRCAness vs. Non-BRCAness) | 3.3 | 1.3–10.1 | 0.008 | 6.3 | 1.9–29.0 | 0.002 |
Chemotherapy | (Anthra vs. Non-anthra) | 0.2 | 0.1–0.7 | 0.02 | 0.1 | 0.02–0.7 | 0.03 |
(Anthra vs. No Treatment) | 0.6 | 0.2–1.3 | 0.17 | 0.2 | 0.1–0.4 | 0.0002 |
HR, hazard ratio; CI, confidence interval; vs., versus; Anthra, Anthracycline-based adjuvant chemotherapy; non-Anthra, Non-anthracycline-based adjuvant chemotherapy.