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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Physiol Behav. 2016 Sep 1;167:16–27. doi: 10.1016/j.physbeh.2016.08.036

Fig. 4.

Fig. 4

Pharmacological inhibition of G9a/CB1R or genetic ablation of CB1R fails to rescue 5-AzaC-induced caspase-3 activation in P7 mice. (A) The mice were pre-treated with Bix (1 mg/kg) or vehicle for 30 min and then exposed to 5-AzaC (5 mg/kg). The CC3 levels in cytosolic extracts of the hippocampus (HP) and neocortex (NC) were determined by Western blot analysis. (B) P7 CB1RWT mice were pre-treated with SR (1 mg/kg) or vehicle for 30 min, and P7 CB1RKO mice were exposed to 5-AzaC (5 mg/kg). The CC3 levels in cytosolic extracts of the hippocampus (HP) were determined by Western blot analysis. β-actin was used as a loading control. Error bars, SEM (n = 10 pups/group) (*p < 0.01 vs. vehicle).