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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Clin Immunol. 2016 Jul 16;172:65–71. doi: 10.1016/j.clim.2016.07.007

Figure 3.

Figure 3

Liver pathology in pristane-treated mice. B6 (A–D) and BALB/c (E–F) mice were treated with pristane and 10 months later, liver was formalin-fixed and stained with hematoxylin & eosin. Controls were untreated B6 mice (G–H). A, liver underlying a pristane-induced lipogranuloma (Lipo) showing coagulative necrosis (yellow arrowhead). Examination of the area within the red box at high power (B) showing coagulative necrosis and cell death (yellow arrowhead). C, bile stasis (yellow arrowhead). D, extensive bile duct proliferation (yellow arrowhead) and lymphoplasmacytic inflammatory infiltrates (white arrow). E (low power) and F (high power), lymphoplasmacytic infiltrates in a peri-portal distribution (yellow arrowheads) in liver tissue from a 10-month pristane-treated BALB/c mouse. Plasma cells are indicated by *. G (low power) and H (high power), absence of liver inflammation in tissue from an untreated B6 mouse.