Table 3.
Univariate association between the seven fetal SNP alleles used in the composite fetal imprinted gene allele score and maternal mean arterial blood pressures at 28 weeks gestation in HAPO Study participants with European ancestry.
Gene | Fetal SNP | Directly Genotyped or Imputed? | Parental Transmission | Risk Allele | n | Standardised β-Coefficient | Standard Error of the β-Coefficient | p-value |
---|---|---|---|---|---|---|---|---|
FAM99A | rs1489945 | Genotyped | maternal | C | 999 | −0.99 | 0.50 | 0.046 |
DLK1 | rs10139403 | Genotyped | maternal | G | 1,067 | 0.11 | 0.60 | 0.860 |
DLK1 | rs12147008 | Genotyped | maternal | T | 1,099 | 0.52 | 0.81 | 0.520 |
H19 | rs217222 | Imputed | paternal | G | 1,149 | −0.14 | 0.62 | 0.823 |
SNRPN | rs1453556 | Genotyped | Paternal | G | 1,016 | 0.01 | 0.53 | 0.988 |
IGF2, INS | rs6356 | Genotyped | Paternal | A | 1,020 | 0.21 | 0.50 | 0.679 |
NNAT | rs6066671 | Genotyped | Paternal | A | 986 | 0.25 | 0.50 | 0.613 |