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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Hypertension. 2016 Oct 17;68(6):1385–1392. doi: 10.1161/HYPERTENSIONAHA.116.08242

Figure 7. Role of Brain Renin.

Figure 7

(A) Total renin mRNA expression in PVN (n=9 per group), RVLM (n=9 per group), SFO (n=8 control, n=9 renin-bNull), ARC (n=9 per group) and NTS (n=9 per group). *, P<0.05 vs control. (B) Acute BP effect of i.c.v. infusion of aliskiren over 30 min (control n=5, renin-bNull n=7). *, P<0.05 vs control; #, P<0.05 vs. i.c.v. vehicle. (C) Model illustrating coordinate regulation of renin-a expression by renin-b in the brain under normal (left) and hypertension-inducing conditions (right).