Table 3.

Potential predictors for disease specific survival in patients with midgut neuroendocrine tumor

	Univariate analysis			MFS (multivariate analysis)
	HR	95% CI	P value	HR	95% CI	P value
Sex	0.96	0.43–2.13	0.920	0.61	0.35–1.05	0.072
Age	1.10	1.05–1.15	<0.001*
pT2				1.10	0.13–9.49	0.930
pT3	1.52	0.33–7.04	0.586	1.26	0.17–9.35	0.823
pT4	2.80	0.60–12.85	0.185	1.02	0.13–7.88	0.988
LN metastasis	1.19	0.35–4.05	0.775	0.98	0.47–2.05	0.967
MTD	11.89	1.60–88.45	0.016*	4.58	1.89–11.11	0.001*
Liver metastasis	5.08	1.19–21.75	0.028*
Histologic grade	0.71	0.16–3.21	0.653

Abbreviations: MSF, metastasis-free survival; HR, hazard ratio; CI, confidence interval; LN, lymph node; MTD, mesenteric tumor deposit.

^*p<0.05.

Note: Age was entered as a continuous variable; pT3 and pT4 tumors were compared to combined pT1 and pT2 tumors in the univariate analysis; pT2, pT3, and pT4 tumors were compared to T1 in the multivariate analysis; the multivariate analysis was stratified by grade. WHO grade 1 was the reference category for histologic grade in the univariate analysis.