Table 2.
Mean and standard deviation of severity score, by HPV type group and case/control status in the validation set
| HPV Type Group | Case-Ctl | Obs (N) | Mean | Std Dev |
|---|---|---|---|---|
| Negative | <CIN2 | 233 | 0.40 | 0.13 |
|
| ||||
| CIN2+ | 36 | 0.51 | 0.19 | |
|
| ||||
| 35/39/51/56/59/66/68 | <CIN2 | 68 | 0.45 | 0.14 |
|
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| CIN2+ | 39 | 0.53 | 0.15 | |
|
| ||||
| 31/33/52/58 | <CIN2 | 34 | 0.43 | 0.14 |
|
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| CIN2+ | 75 | 0.57 | 0.17 | |
|
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| 18/45 | <CIN2 | 32 | 0.40 | 0.14 |
|
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| CIN2+ | 49 | 0.61 | 0.17 | |
|
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| 16 | <CIN2 | 35 | 0.46 | 0.18 |
|
| ||||
| CIN2+ | 216 | 0.58 | 0.18 | |
HPV-negative women overall tended to have lower severity scores than HPV-positive women (p = 0.002 among cases, and p = 0.01 among controls). Among HPV-positive women, severity scores were not associated with HPV type groups, when stratified by <CIN2/≥CIN2 outcome.