Figure 2.
Lymph nodes in MELF cases often showed the sinus histiocyte-like pattern of metastasis (A, B), which was occasionally confirmed at the time of the original pathologic diagnosis with cytokeratin immunostaining (C). Numerous larger glandular metastases were identified showing cystic (D) or solid patterns (E). Glandular metastases in MELF cases also occasionally displayed discohesive areas reminiscent of the sinus histiocyte-like pattern (F).