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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Anesthesiology. 2017 Jan;126(1):74–84. doi: 10.1097/ALN.0000000000001383

Table 1.

Timeline of procedures for subjects.

Infant Age Procedure
Day 5 Removed from group with dam
Day 6 First ISO or sham exposure
Day 9 Second ISO or sham exposure
Day 12 Third ISO or sham exposure
Day 14 IBAS test Release back to social group
Day 30 IBAS test (removed from social group with dam day before) Release back to social group
3 months Free play/Human Intruder/Novel object tests (removed from social group with dam day before)
Released back to social group
12 months Weaned from natal group; placed in new social group
Home cage observations (started approximately 1–2 days after moved to new group)
Human Intruder /Novel object test (approximately 1–2 weeks after end of focal observations)

Abbreviations:

IBAS: Infant Behavior Assessment Scale

ISO: Isoflurane