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. Author manuscript; available in PMC: 2017 Aug 18.
Published in final edited form as: Cell Chem Biol. 2016 Aug 11;23(8):978–991. doi: 10.1016/j.chembiol.2016.06.016

Figure 6. Inhibition of cytochrome bc1 by Inz-5 prevents adaptation to certain carbon sources.

Figure 6

A) Growth of ~104 C. albicans SC5314 cells on agar plates containing various carbon sources in the presence of a filter disc containing DMSO (top) or 10μg Inz-5 dissolved in DMSO (bottom). B) Co-culture of BFP-labeled C. albicans and GFP-tubulin-labeled mouse bone-marrow-derived macrophages. C) Quantification of effects on filamentation observed in (B); data from two independent experiments; error bars indicate S.E.M. D) Relative fungal survival quantified by resazurin dye reduction after 14 hr co-culture at MOI of 0.125 in the presence of mouse bone marrow-derived macrophages. Data from two independent experiments; error bars indicate S.E.M.