Table 2.

PDT dose, mean singlet oxygen concentration (Mean [¹O₂]_rx), tumor re-growth factor and cure index (CI) calculated for each PDT treatment condition.

In-air fluence (J/cm2)	φair (mW/cm2)	Timea (s)	Pre-HPPHb (µM)	Post-HPPHc (µM)	PDT dosed (µM J/cm2)	Mean [1O2]rx (µM)	k (1/days)	CI
30	20	1500	0.32 ± 0.20	0.24 ± 0.09	8.03 ± 5.10	0.34 ± 0.20	0.366 ± 0.012	0.04 ± 0.03
	75	400	0.15 ± 0.03	0.10 ± 0.04	3.77 ± 0.81	0.15 ± 0.03	0.372 ± 0.010	0.02 ± 0.03
50	20	2500	0.45 ± 0.07	0.30 ± 0.05	17.96 ± 2.66	0.67 ± 0.09	0.342 ± 0.013	0.10 ± 0.03
	75	667	0.40 ± 0.13	0.26 ± 0.09	16.10 ± 5.49	0.51 ± 0.13	0.365 ± 0.040	0.04 ± 0.09
	150	333	0.22 ± 0.13	0.14 ± 0.06	8.85 ± 5.37	0.28 ± 0.13	0.363 ± 0.044	0.04 ± 0.06
135	50	2700	0.34 ± 0.12	0.18 ± 0.05	30.43 ± 10.99	0.82 ± 0.28	0.292 ± 0.012	0.23 ± 0.03
	75	1800	0.32 ± 0.16	0.13 ± 0.10	28.82 ± 14.55	0.76 ± 0.36	0.318 ± 0.027	0.16 ± 0.07
	150	900	0.33 ± 0.18	0.14 ± 0.07	30.40 ± 19.23	0.72 ± 0.36	0.322 ± 0.042	0.15 ± 0.10
250	50	5000	0.37 ± 0.22	0.10 ± 0.02	48.52 ± 29.16	1.00 ± 0.58	0.186 ± 0.020	0.51 ± 0.05
	75	3333	0.33 ± 0.09	0.09 ± 0.04	43.64 ± 12.85	0.89 ± 0.25	0.245 ± 0.027	0.36 ± 0.07
	150	1667	0.31 ± 0.21	0.07 ± 0.01	42.22 ± 30.38	0.83 ± 0.55	0.298 ± 0.037	0.22 ± 0.11
350	50	7000	0.46 ± 0.10	0.10 ± 0.01	70.50 ± 16.49	1.25 ± 0.28	0.000 ± 0.000	1.00 ± 0.00
	75	4667	0.51 ± 0.13	0.08 ± 0.01	79.99 ± 27.52	1.39 ± 0.45	0.000 ± 0.000	1.00 ± 0.00
	150	2334	0.36 ± 0.17	0.06 ± 0.02	58.04 ± 29.38	0.98 ± 0.44	0.204 ± 0.017	0.46 ± 0.04
350	150	2334	0	0	0	0	0	0
0	0	0	0	0	0	0	0.380 ± 0.045	0

^aPDT exposure time

^bHPPH concentration prior to PDT

^cHPPH concentration after PDT

^dPDT dose is calculated by the time integral of the product of local photosensitizer concentration and light fluence rate (φ).