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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Hepatology. 2016 Jul 27;65(2):647–660. doi: 10.1002/hep.28681

Figure 4. Biopsies from two representative WISP-R subjects with consistently normal liver test profiles as shown in Figure 2A.

Figure 4

Biopsies from two representative WISP-R participants (Subjects 4 and 5; liver test profiles shown in Figure 2A) are shown. A scale bar is in the upper left corner of the panels.

Trichrome-stained sections of entire Yr 0 and Yr 5 biopsies captured at low magnification from Subject 4 (A) and 5 (C) show intact architecture. Higher magnification of representative areas of Yr 0 and Yr 5 biopsies are shown (B and D). Each inset shows higher magnification of representative portal tracts: all are devoid of inflammation. Finally, note that the thinner, 18 gauge Yr 0 biopsy is fragmented whereas the thicker, 16 gauge, Yr 5 biopsy is not (A).