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. Author manuscript; available in PMC: 2017 Dec 15.

Published in final edited form as: Clin Cancer Res. 2016 Jun 15;22(24):6247–6255. doi: 10.1158/1078-0432.CCR-15-2738

Fig 5 — (A) Immunohistochemical analysis of MHC class II protein expression in adrenocortical tumors. Row a: adenoma; row b: stage I carcinoma; row c: stage III carcinoma. Note high expression of HLA-DRA and HLA-DPA1 in the adenoma and low expression in the two carcinomas. CD68 is a cytoplasmic marker for cells of the macrophage lineage. (B) Immunohistochemical analysis reveals HLA-DPA1 expression by adrenocortical tumor cells in two pediatric ACTs: (a) ACT047 and (b) ACT048 (Magnification, 100×; inset, 400×).

Fig 5 — (A) Immunohistochemical analysis of MHC class II protein expression in adrenocortical tumors. Row a: adenoma; row b: stage I carcinoma; row c: stage III carcinoma. Note high expression of HLA-DRA and HLA-DPA1 in the adenoma and low expression in the two carcinomas. CD68 is a cytoplasmic marker for cells of the macrophage lineage. (B) Immunohistochemical analysis reveals HLA-DPA1 expression by adrenocortical tumor cells in two pediatric ACTs: (a) ACT047 and (b) ACT048 (Magnification, 100×; inset, 400×).