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. 2016 Nov;4(22):443. doi: 10.21037/atm.2016.11.06

Table 3. Predictive parameters of ODIox for different categories of OSAHS severity.

Predictive parameters Mild Moderate Severe
ODI ≥5
   Se (%) 65.0 98.0 100.0
   Sp (%) 16.6 27.9 36.0
   PPV (%) 11.9 31.6 52.2
   NPV (%) 73.7 97.6 100.0
   Probability (+)/(−) (%) 81/19 78.7/21.3 79/21
   LR (+)/(−) 0.8/2.1 1.36/0.07 1.56/0
   OR (95% CI) 0.4 (0.16–0.9) 18.9 (2.5–141.8) 2.1 (1.7–2.5)
   AUC (95% CI) 0.4 (0.29–0.5) 0.63 (0.55–0.71) 0.68 (0.6–0.75)
ODI ≥10
   Se (%) 34.5 90.0 100.0
   Sp (%) 19.5 34.7 48.7
   PPV (%) 6.8 31.9 57.7
   NPV (%) 63.5 91.0 100.0
   Probability (+)/(−) (%) 74/26 71.6/28.4 71.3/28.7
   LR (+)/(−) 0.43/3.35 1.38/0.3 1.95/0
   OR (95% CI) 0.13 (0.05–0.30) 4.8 (1.8–12.8) 2.4 (1.95–2.87)
   AUC (95% CI) 0.27 (0.16–0.38) 0.62 (0.54–0.71) 0.74 (0.67–0.80)
ODI ≥15
   Se (%) 3.4 56.0 97.5
   Sp (%) 32.5 43.5 72.6
   PPV (%) 0.87 25.2 71.4
   NPV (%) 66.2 74.4 97.7
   Probability (+)/(−) (%) 28/72 56.3/43.7 56.3/43.7
   LR (+)/(−) 0.05/2.30 0.99/1.00 3.56/0.03
   OR (95% CI) 0.017 (0.02–0.13) 0.98 (0.51–1.87) 106.2 (24.6–457.9)
   AUC (95% CI) 0.18 (0.12–0.25) 0.498 (0.40–0.59) 0.85 (0.8–0.9)

ODI, oxygen desaturation index; ODIox, ODI of oximetry; OSAHS, obstructive sleep apnea/hypopnea syndrome; Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value; LR, likelihood ratio; OR, odds ratio; CI, confidential interval; AUC, area under the ROC curve.