Skip to main content
. Author manuscript; available in PMC: 2016 Dec 16.
Published in final edited form as: J Med Genet. 2014 Oct 3;51(12):789–796. doi: 10.1136/jmedgenet-2014-102552

Table 1.

BRAF c.1799T>A p.Val600Glu mutation and MLH1 promoter region methylation in MLH1 mutation carriers and sporadic MLH1 loss cancers

Tumour Status Mutant BRAF
AND MLH1
methylation
wt BRAF
AND normal
MLH1
Mutant BRAF
AND normal
MLH1
wt BRAF AND
MLH1
methylation
MLH1 mutation carriers tumours n = 71 0 66 (92.9%) 1 (1.4%) 4 (5.6%)
MMR deficient sporadic tumours n = 73 46 (63.0%) 7 (9.6%) 2 (2.7%) 18 (24.7%)