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Disrupted functional networks to sgACC in MDD patients. Two-sample t-tests were used to identify the significant differences in functional connectivity between MDD and HC groups. The significance was determined using Gaussian random field (GRF) correction p < 0.05 (z > 2.3). The functional connectivity analyses identified disrupted functional connections of posterior insula, middle and inferior temporal gyrus, lingual gyrus and cerebellum to sgACC.
