Table 1.
Demographics and clinical characteristics of the subjects used in the present study.
| Subjects | MDD patients | Healthy controls | P value |
|---|---|---|---|
| Number of subjects | 34 | 34 | |
| Age (mean ± SD) | 29.88 ± 7.070 | 29.71 ± 7.086 | 0.918 |
| Gender (male: female) | 14:20 | 15:19 | 0.806 |
| Years of education | 13.20 ± 3.540 | 14.18 ± 2.167 | 0.171 |
| (mean ± SD) | |||
| HDRS scores (mean ± SD) | 32.91 ± 7.025 | ||
| Age of onset (years) | 25.44 ± 7.386 | ||
| Duration of illness (months) | 53.41 ± 61.185 | ||
| Episodes (n, patients) | |||
| First | 21 | ||
| Recurrence | 13 | ||
| Family history of MDD | 11 | ||
| (n, patients) | |||
| Medication (n, patients) | |||
| Medication-free | 23 | ||
| On-medication | 11 | ||
| SSRI antidepressant | 8 | ||
| SNRI antidepressant | 1 | ||
| NaSSA antidepressant | 1 | ||
| Melatonergic antidepressant | 1 |
Note: Pearson’s chi-squared test was used for gender comparison. Two-sample t-tests were used for age, education comparisons. HDRS, Hamilton Depression Rating Scale scores. SSRI, selective serotonin reuptake inhibitor; SNRI, serotonin norepinephrine reuptake inhibitor; NaSSA, noradrenergic and specific serotonergic antidepressant.