Table 22:

Menstrual Blood Loss Improvement by Follow-Up Time: LNG-IUS vs. Usual Medical Therapy

Author, Year	Follow-Up	MBL Comparison: UMT vs. LNG	P
Irvine et al, 199899	1 mo	LNG bettera	.02
Kaunitz et al, 201097	3 mo	LNG betterb	< .001
Reid and Virtanen-Kari, 200598		LNG bettera	< .001
Irvine et al, 199899		LNG bettera	.03
Kaunitz et al, 201097	6 mo	LNG betterb	< .001
Reid and Virtanen-Kari, 200598		LNG bettera	< .001
Shaaban et al, 201195	1 y	LNG bettera	< .001

Abbreviations: LNG, levonorgestrel-releasing intrauterine system; MBL, menstrual blood loss; mo, month; PBAC, pictorial blood loss assessment chart; UMT, usual medical therapy; y, year.

^aDifference between groups in final PBAC score or mL (mean or median).

^bDifference between groups in median change in MBL from baseline.