Figure 5.

Multiple linear regression analysis. The vertical axis shows the percentage of the protein solvent accessibility variance (R² values) that explained by models that include different combinations of variables as indicated by shaded squares in the matrix. Each model combine different parameters indicated by filled squares on the same row and associated the R² value on the left of the row. Overfitting was tested for models using 5 variables (see Figure 6 and corresponding section). HSA, SCE, BSU, ECO, TGA denote, respectively, H. sapiens, S. cerevisiae, B. subtilis, E. coli and T. gammatolerans. The structural data sets were analyzed.