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. 2016 Oct 15;44(22):10862–10878. doi: 10.1093/nar/gkw917

Table 2. Catalytic parameters of RET1 deletion mutants.

	UTP				RNA
Mutants	K_m (μM)	k_cat (min⁻¹)	k_cat/K_m (min⁻¹μM⁻¹)	Relative k_cat/K_m	K_m (μM)	k_cat (min⁻¹)	k_cat/K_m (min⁻¹μM⁻¹)	Relative k_cat/K_m
RET1	8.5 ± 1.3	15.5 ± 0.8	1.8	1	0.53 ± 0.1	23.5 ± 1.7	44.3	1
RET1ΔC	9.8 ± 2.5	22.7 ± 2.1	2.3	1.3	12.4 ± 1.7	29.7 ± 2.1	2.3	0.05
RET1ΔN	11.1 ± 0.8	16.7 ± 0.5	1.5	0.83	0.024 ± 0.006	18.3 ± 1.1	763	17.2
RET1ΔNC	6.6 ± 0.5	23.5 ± 0.6	3.6	2.0	4.5 ± 0.8	32.5 ± 2.0	7.2	0.16
RET1ΔNC RRR	6.1 ± 1.5	9.5 ± 0.7	1.6	0.89	22.6 ± 13.7	19.2 ± 5.3	0.85	0.019