Figure 7. Cumulative penetrance of individual phenotypes in mutant embryos.

Data from the global analysis of the frequency of phenotype terms (see Materials and Methods) was plotted to show the cumulative penetrance score for each of the phenotype categories observed (i.e. the overall sum of the penetrance scores recorded for the lines showing the phenotype). The Mammalian Phenotype Ontology terms assigned during embryo phenotyping were summarised using the intermediate level DMDD ontology slim, and the data was ordered according to the cumulative penetrance score. The colours indicate the contribution of lines falling into each of the distinct penetrance categories to the cumulative penetrance score.