Table 3. Overlap of identified phenotypes between homozygous mutant and wild type embryos within each line.
Mutant lines showing a phenotype shared by at least one homozygous mutant and one wild type embryo are listed, along with the MP term, its MP ID and it penetrance amongst the mutant and wildtype embryos. For each line where an overlap is identified, the ratio of shared phenotypes to the total number of unique phenotypes identified in mutant embryos is also presented.
| Allele | Phenotypes shared by homozygous
mutants and wild type embryos |
MP ID | Penetrance
in mutants |
Penetrance
in wild types |
Ratio of shared:
total mutant phenotypes |
|---|---|---|---|---|---|
| Adamts3<tm1b(KOMP)Wtsi> | abnormal forebrain morphology | MP:0000783 | 2/7 | 1/3 | 2/44 |
| abnormal Mullerian duct topology | MP:0013852 | 1/7 | 1/3 | ||
| Adcy9<tm1b(EUCOMM)Wtsi> | abnormal Mullerian duct morphology | MP:0003826 | 1/8 | 1/3 | 2/20 |
| blood in lymph vessels | MP:0013971 | 1/8 | 1/3 | ||
| Celf4<tm1a(EUCOMM)Wtsi> | blood in lymph vessels | MP:0013971 | 1/5 | 1/3 | 1/7 |
| Chtop<tm1a(EUCOMM)Wtsi> | abnormal forebrain morphology | MP:0000783 | 4/4 | 1/3 | 1/95 |
| Cir1<tm3a(KOMP)Wtsi> | additional anastomosis between
intracranial vertebral arteries |
MP:0014003 | 1/3 | 1/2 | 1/29 |
| Nsun2<tm1a(EUCOMM)Wtsi> | absent ductus venosus valve | MP:0013876 | 1/6 | 1/2 | 1/37 |
| Psph<tm1a(EUCOMM)Hmgu> | blood in lymph vessels | MP:0013971 | 1/8 | 1/3 | 1/109 |
| Tcf7l2<tm1a(EUCOMM)Wtsi> | absent ductus venosus valve | MP:0013876 | 2/5 | 1/4 | 3/32 |
| enlarged liver sinusoidal spaces | MP:0000602 | 2/5 | 1/4 | ||
| abnormal eye muscle morphology | MP:0003686 | 3/5 | 1/4 | ||
| Traf6<tm2a(EUCOMM)Wtsi> | blood in lymph vessels | MP:0013971 | 4/9 | 1/5 | 1/39 |
| Unk<tm1a(KOMP)Wtsi> | absent ureter | MP:0003722 | 2/5 | 1/2 | 2/10 |
| absent kidney | MP:0000520 | 2/5 | 1/2 |