Table 1.
Causes of RhD immunization in women with partial D
| Genotype | Pregnant women |
||
|---|---|---|---|
| 1 | 2 | 3 | |
| DNB category | RHD category Va | RHD category Va | |
| Phenotype | CcEe | CCee | Ccee |
| Pregnancies | 1. miscarriage 2. uneventful 3. RhD+, DAT 1+ 4. RhD+, DAT 3+ |
1. miscarriage 2. RhD+, DAT− 3. miscarriage 4. RhD+, DAT− |
1. uneventful 2. RhD+, DAT– 3. RhD+, DAT+ 4. RhD variant, DAT– 5. RhD–, DAT– 6. RhD+, DAT+ |
| Transfusion | yes after 2nd pregnancy* |
no | yes after 1st pregnancy* |
| Pregnancy† | 3rd | 2nd | 3rd |
| Cause of immunization | unclear (pregnancy or transfusion) |
pregnancy | unclear (pregnancy or transfusion) |
*
Women received RhD positive RBCs.
†
Pregnancy in which anti-D antibody was detected.