Table 7.
CheckMate 040 dose-escalation cohort (n=48) investigator-assessed best overall response (RE CIST v1.1)
Uninfected (n=23) | HCV (n=10) | HBV (n=15) | Total (n=48) | |
---|---|---|---|---|
Objective response, n (%) | 3 (13) | 3 (30) | 1 (7) | 7 (15) |
CR | 2 (9) | 1 (10) | 0 | 3 (6) |
PR | 1 (4) | 2 (20) | 1 (7) | 4 (8) |
SD | 13(57) | 5 (50) | 6 (40) | 24 (50) |
PD | 6 (26) | 2 (20) | 7 (47) | 15 (31) |
Not evaluable | 1 (4) | 0 | 1 (7) | 2 (4) |
Ongoing response, n (%) | 1 (33) | 0 | 0 | 1 (14) |
Reproduced with permission from El-Khoueiry AB, et al. [29]