Table 4. Multiple-ordinal logistic regression models per clinical vignette.
Vignette 1a | Vignette 2b | |||||
---|---|---|---|---|---|---|
Variables tested | Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value |
Cancer-oriented consent (vs general consent) | 0.95 | 0.74–1.20 | 0.68 | — | — | — |
Single review of the patient’s chart (vs several reviews) | 1.37 | 1.07–1.74 | 0.011 | — | — | — |
Genetic analyses on the biospecimens (vs blood protein analysis) | 0.97 | 0.76–1.23 | 0.77 | — | — | — |
Oral swabbing (vs blood sample) | — | — | — | 1.32 | 1.04–1.67 | 0.021 |
No follow-up of patients (vs follow-up) | — | — | — | 1.36 | 1.07–1.73 | 0.012 |
Local project (vs international) | — | — | — | 0.87 | 0.69–1.10 | 0.24 |
Categories of age (years), (vs ⩾75) | 0.004 | <0.001 | ||||
<40 | 1.72 | 1.18–2.49 | 0.005 | 1.89 | 1.31–2.74 | 0.001 |
40–59 | 1.68 | 1.20–2.35 | 0.003 | 1.66 | 1.19–2.30 | 0.003 |
60–74 | 1.60 | 1.16–2.22 | <0.001 | 1.80 | 1.30–2.48 | <0.001 |
Male gender (vs female) | 1.03 | 0.80–1.32 | 0.84 | 1.07 | 0.84–1.37 | 0.59 |
Country of birth (vs other country) | 0.058 | 0.032 | ||||
Switzerland | 1.56 | 1.07–2.26 | 0.020 | 1.52 | 1.05–2.19 | 0.026 |
Other European countries | 1.49 | 1.02–2.19 | 0.041 | 1.64 | 1.12–2.39 | 0.010 |
Level of education (vs elementary school/apprenticeship) | 0.19 | 0.059 | ||||
Secondary school | 0.94 | 0.64–1.40 | 0.78 | 1.38 | 0.93–2.07 | 0.11 |
Professional school/university | 1.29 | 0.99–1.70 | 0.06 | 1.33 | 1.02–1.74 | 0.034 |
At least one child (vs no child) | 1.30 | 0.96–1.76 | 0.09 | 1.40 | 1.04–1.88 | 0.027 |
Excellent/very good health status (vs good/fair/poor) | 0.90 | 0.68–1.19 | 0.47 | 0.97 | 0.74–1.28 | 0.84 |
Opinion on research (from 'very negative' to 'very positive') | 1.82 | 1.53–2.17 | <0.001 | 1.93 | 1.63–2.30 | <0.001 |
Past participation in clinical studies (vs no participation) | 1.71 | 1.28–2.29 | <0.001 | 1.53 | 1.15–2.03 | 0.004 |
Positive opinion on genetic research (vs negative or no opinion) | 3.29 | 2.47–4.38 | <0.001 | 3.36 | 2.53–4.46 | <0.001 |
Blood or organ donor (vs not) | 1.53 | 1.19–1.97 | 0.001 | 1.90 | 1.47–2.44 | <0.001 |
Abbreviation: CI, confidence interval.
Among respondents, 989 of 1,108 (89.3%) had no missing data.
Among respondents, 992 of 1,102 (90.0%) had no missing data.