Table 4. Multiple-ordinal logistic regression models per clinical vignette.

	Vignette 1a			Vignette 2b
Variables tested	Odds ratio	95% CI	P-value	Odds ratio	95% CI	P-value
Cancer-oriented consent (vs general consent)	0.95	0.74–1.20	0.68	—	—	—
Single review of the patient’s chart (vs several reviews)	1.37	1.07–1.74	0.011	—	—	—
Genetic analyses on the biospecimens (vs blood protein analysis)	0.97	0.76–1.23	0.77	—	—	—
Oral swabbing (vs blood sample)	—	—	—	1.32	1.04–1.67	0.021
No follow-up of patients (vs follow-up)	—	—	—	1.36	1.07–1.73	0.012
Local project (vs international)	—	—	—	0.87	0.69–1.10	0.24
Categories of age (years), (vs ⩾75)			0.004			<0.001
<40	1.72	1.18–2.49	0.005	1.89	1.31–2.74	0.001
40–59	1.68	1.20–2.35	0.003	1.66	1.19–2.30	0.003
60–74	1.60	1.16–2.22	<0.001	1.80	1.30–2.48	<0.001
Male gender (vs female)	1.03	0.80–1.32	0.84	1.07	0.84–1.37	0.59
Country of birth (vs other country)			0.058			0.032
Switzerland	1.56	1.07–2.26	0.020	1.52	1.05–2.19	0.026
Other European countries	1.49	1.02–2.19	0.041	1.64	1.12–2.39	0.010
Level of education (vs elementary school/apprenticeship)			0.19			0.059
Secondary school	0.94	0.64–1.40	0.78	1.38	0.93–2.07	0.11
Professional school/university	1.29	0.99–1.70	0.06	1.33	1.02–1.74	0.034
At least one child (vs no child)	1.30	0.96–1.76	0.09	1.40	1.04–1.88	0.027
Excellent/very good health status (vs good/fair/poor)	0.90	0.68–1.19	0.47	0.97	0.74–1.28	0.84
Opinion on research (from 'very negative' to 'very positive')	1.82	1.53–2.17	<0.001	1.93	1.63–2.30	<0.001
Past participation in clinical studies (vs no participation)	1.71	1.28–2.29	<0.001	1.53	1.15–2.03	0.004
Positive opinion on genetic research (vs negative or no opinion)	3.29	2.47–4.38	<0.001	3.36	2.53–4.46	<0.001
Blood or organ donor (vs not)	1.53	1.19–1.97	0.001	1.90	1.47–2.44	<0.001

Abbreviation: CI, confidence interval.

^aAmong respondents, 989 of 1,108 (89.3%) had no missing data.

^bAmong respondents, 992 of 1,102 (90.0%) had no missing data.