Table 4. Summary of allele from founders with B2m-TALEN-mediated modifications.
Founder No. | Target site mutations | Sequenced colonies |
---|---|---|
T1 | del 1 bp (T) | 1 |
del 2 bp (TT) | 11 | |
del 2 bp (AC) | 1 | |
del 16 bp | 3 | |
T2 | del 1 bp | 5 |
del 7 bp | 4 | |
WT | 6 | |
T3 | del 1 bp | 9 |
del 7 bp | 3 | |
del 16 bp | 2 | |
WT | 5 | |
T4 | del 2 bp | 7 |
WT | 14 | |
T5 | del 11 bp | 4 |
del 25 bp | 13 | |
T6 | del 1 bp (A) | 6 |
WT | 16 | |
T7 | WT | 20 |
Del: deletion; WT: wild type.