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. 2016 Dec 16;6:39129. doi: 10.1038/srep39129

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(a) The 2-aminopyridine derivatives substituted at the third position; (b) the regioselective hydroxylation of 2-aminopyridines substituted at the fourth position (X = CH₃, Cl, F); (c) the 2-aminopyridines substituted at the sixth position.