Table 3. The bioconversion features of pyridine and pyrazine derivatives for which reactions products were detectable.
| Substrate |
Product |
|||
|---|---|---|---|---|
| Name | [M+H]+ | [M+H]+ | NMR | Name/Possible outcome |
| Pyridine | 80 | 96 | − | Hydroxylated at the 1-position |
| 2-Methylpyridine | 94 | 110 | − | Hydroxylated at the 1-position |
| 3-Methylpyridine | 94 | 110 | − | Hydroxylated at the 1-position |
| 4-Methylpyridine | 94 | 110 | − | Hydroxylated at the 1-position |
| Pyrazine | 81 | 97 and 113 | + | pyrazine-1-oxide and pyrazine-1,4-dioxide |
For the NMR analysis approximately 10 mg of purified bioconversion product was used.