Figure 1. HQT ameliorates DSS-induced acute colitis in mice.

Mice were administered regular water (control) or 3.5% DSS for 7 days followed by treatment with HQT for 7 days. (a) Body weight, as a percent of starting weight, assessed daily. (b,c) Colon length, measured at day 14 after treatment. (d) Colonic MPO activity analysis. The results are expressed as units of MPO activity per mg of protein. (e,f) Representative H&E-stained distal colonic sections and histological scores, assessed at day 14 after treatment (magnification, x100). Results are expressed as means ± SD of three independent experiments; n = 8 mice per group. ^*p < 0.05, ^**p < 0.001 vs. the control group; ^△p < 0.05, ^△△p < 0.001 vs. DSS-treated mice. MPO, myeloperoxidase.