Figure 5. Proposed folding pathway of concatenated HP0242.

The secondary structure elements are colour-ramped from blue to red from the N- to the C-termini with the helices numbered from one to four for the N-terminal half and those of the C-terminal half are numbered in the same way with additional apostrophes. The tryptophan side-chains are shown explicitly in the cartoon representation. In the intermediate (I) and denatured (D) states, the partially unfolded helices are shown in dashed cylinders.