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Interruption of NAO therapy before surgery
| Dabigatran | Rivaroxaban | Apixaban | ||||
|---|---|---|---|---|---|---|
| Renal function | Low risk | High risk | Low risk | High risk | Low risk | High risk |
| ClCr 80ml/min | 24h | 48h | 24h | 48h | 24h | 48h |
| ClCr 50–80ml/min | 36 | 72 | 24h | 48h | 24h | 48h |
| ClCr 30–49ml/min | 48 | 96 | 24h | 48h | 24h | 48h |
| ClCr 15–30ml/min | Not indicated | Not indicated | 36h | 48h | 36 | 48h |
| ClCr <15ml/min | ||||||
no official data are available
