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. 2016 Dec 15;17:532. doi: 10.1186/s12859-016-1391-0

Fig. 3.

Fig. 3

Features of the switch-points defined in SwitchFinder: Growth, Decay, Spike and Cleft. Features are assigned to the switch-points to capture meaningfull properties of the time-series. The feature Growth is assigned to the switches of types trough, if the corresponding Slope is greater than the Threshold with the default value threshold_growth. The user is able to adjust the Threshold for selecting more striking Growth-effects. The feature Decay is defined similarly. The higher-order feature Spike is assigned to the switch, designated with Decay, if its left-hand side neighbour has the feature Growth and the absolute difference Dif in the gene expression levels of the neighbouring switches is smaller than the Threshold with the default threshold_dif. The aim is to select a really spiking behaviour: after a rapid growth, rapid decay to almost the same level occurs. The feature Cleft designates the opposite behaviour: after a decay, growth to almost the same level occurs