Figure 1.

A comparison of nerve localization during embryonic and early postnatal crown morphogenesis of the mouse mandibular incisor, and 2-rooted first molar. Tooth innervation takes place in a stereotypic manner in both tooth types, and is linked to the advancing tooth histomorphogenesis and dental cell differentiation. See main text for a description of the figure. (A, F) initiation stage; (B), bud stage; (C, G) cap stage; (D, E, H, I) bell stage. Abbreviations: cm, condensed dental mesenchyme; de, dental epithelium; dp, dental pulp; p, dental papilla; ek, enamel knot; pm, presumptive dental mesenchyme. Nerve fibers are indicated in black. This schematic is based on data from previous reports.^{32,23,13,25,26}